If you want to be logged in with your user certificate and PIN from your Yubikey insted of the ad-user password… thats what is already possible. Set “Edit first factor” in the Global user Settings or specific organisational unit / user setting for Windows application to “Smartcard”.
PS: If you want to let the users use the web app, you can set the FIDO2 for web application.
Is FIDO2 functionality exclusively available when users are operating in Master Key Mode? Given that our users are currently in E2EE Mode, does this imply that FIDO2 cannot be utilized in E2EE Mode?